Prolactin levels

November 6, 2008 at 1:06 pm 5 comments

Thanks to Alecia‘s inspiring graphs, this is the evolution of my PRL.

The worrying story began with the galactorrhea: one day I found out my breasts were producing a milky substance, even though I wasn’t pregnant. Not much, just a few drops and only when pressing around the nipple. That’s why the endo that prescribed me the pill (because of the increased hair on my arms) sent me to the gynaecologist, who asked inmediately for an MRI and there it was! the chickpea. But, apparently, an innocent one.

I was taking the pill, and I was told that the pill sometimes rises the PRL levels. My endo prescribed cabergoline (Dostinex), the usual drug to make prolactin levels return to normal, but as those weren’t worrying enough (neither for her nor for the subsequent endos that I had) I was told to stop.

Then, a few years later, I stopped taking the pill (on purpose) and having the period (not on purpose) and a PRL check showed an alarming increase: 62.79 ng/ml. It was summer of 2007, I was already in Munich, my new gyn told me to take cabergoline (Dostinex) again. PRL dropped, but my period didn’t show up. So she sent me to another endo, who did a thorough hormone analysis in december, found out that the chickpea wasn’t innocent at all and I was sent eventually to the neurosurgeon two months later.

Right after the surgery (and by “right after” I mean “the following day”), the PRL levels dropped to nearly non-existent. Galactorrhea stopped and I got my period back, on a 29-day regular basis.

prl1

(Not all PRL values that I have are shown, but just the most significant ones)

Apparently, my PRL levels were too low to suggest a PRL-producing adenoma, but it was. It produced both PRL and GH.

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Entry filed under: Evolution. Tags: , , , .

Back from H (Hospital, Holidays) “Bad news?” or “Does running affect GH?”

5 Comments Add your own

  • 1. Alecia  |  November 25, 2008 at 8:46 pm

    Fascinating! You did a nice job on your chart. I found that marking the levels were a big help and kept me from digging through the stack(s!) of paperwork I have sitting around the house.

    Like the look of your new blog!

  • 2. magpieandchickpea  |  November 27, 2008 at 12:14 pm

    Thanks, Alecia!!

    You had a great idea with the graphs! It’s very easy to retrieve all information we need/we are interested on, instead of browsing through a pile of papers ….

    I’ll soon post the one with IGF-1 and GH levels.

  • 3. acromegaly  |  December 2, 2008 at 9:10 pm

    Great chart! Good work.

    I’ve got slightly elevated Prolactin too (with my very very high IGF-1). I’m a bloke. Apparently Prolactin can just be elevated at time of stress or depending on the time of day. I read somewhere that about a third of GH-secreting adonema’s also give out prolactin.

    Trys

  • 4. magpieandchickpea  |  December 3, 2008 at 8:08 am

    Hi Trys! Before surgery noone thought my adenoma was secreting PRL as well as GH because prolactin levels weren’t high enough (whatever that means for them). After removing the “chickpea” the histology study showed it had produced both hormones. Surprise!. Anyway, it was successfully removed and after surgery my PRL values returned to normal (yes!) and galactorrhea is gone for good! (yes! yes! yes!) with all the things that mean for a girl (having the period back, for instance). My be your adenoma is also producing PRL.

  • 5. acromegaly  |  December 4, 2008 at 9:02 am

    Yes, my adonoma is probably producing some PRL, but there again a lot of them do. It’s not worth getting too worried about.

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