Archive for November, 2008

“Bad news?” or “Does running affect GH?”

sad_cartoonThis morning I went to pick up my last bloodwork results and I was shocked to see this:

IGF-1 309 ng/ml (114 – 492)

GH 12.50 µg/l (0 – 6.88)

What is this supposed to mean???

This is a blood test done at the beginning of september. One week later I talked to my endo on the phone and she informed me of the results. She only said, IGF-1 is 309, that’s good. Everything is all right. Call the secretary for an appointment in 3 months for a glucose tolerance test.  I asked if I could have the results printed and she said, whenever you come along, ask for a copy. So I thought everything was all right and I was happy. I called for an appointment for a GTT and that’s scheduled for monday the 1st. I was close to the doctors today and I walked in to ask for a copy of that bloodwork… and then I found that GH is way higher than what it is supposed to be.

Shock.

This, automatically brought me back to the beginning of my condition. For a loong, loooong time, my GH was way too high and my IGF-1 was in the normal range. Every doctor I saw told me not to worry, if IGF-1 is in the normal range, I am not ill. They explained the IGF-1 is a measurement of the GH of the last 24 hours and that GH could be anormally high in some moments of the day. But then, one day, IGF-1 was not in the normal range anymore. They said I had a GH (and PRL) producing tumor (the chickpea) and you know the rest of the story. Noone was able to explain why I had GH anormally high throughout the years with a normal IGF-1 and suddendly, the IGF-1 was not normal anymore.

So, obviously I am concerned. Is this the beginning of the nightmare again? Will it be like this (GH high, IGF-1 normal) for a few years and then, unexpectedly, IGF-1 will rise again and will I be back to the neurosurgeon? The only thing that keeps this little magpie from getting depressed is very simple: I ran to the doctors the day of the test. And when I say “ran” I mean sprint really, really, really fast. Well, I was late… I asked the nurse while she was doing the test and I was still trying to catch my breath if the running would anyhow affect the hormone values, and she said no. I guess she didn’t know what she was taking the blood for, because I’ve read everywhere that sport rises the levels of GH.

The question is, could a sprint be responsible for such a high value of GH?

Next GTT: monday the 1st.

Next Endo appointment: monday the 8th.

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November 26, 2008 at 9:51 am 6 comments

Prolactin levels

Thanks to Alecia‘s inspiring graphs, this is the evolution of my PRL.

The worrying story began with the galactorrhea: one day I found out my breasts were producing a milky substance, even though I wasn’t pregnant. Not much, just a few drops and only when pressing around the nipple. That’s why the endo that prescribed me the pill (because of the increased hair on my arms) sent me to the gynaecologist, who asked inmediately for an MRI and there it was! the chickpea. But, apparently, an innocent one.

I was taking the pill, and I was told that the pill sometimes rises the PRL levels. My endo prescribed cabergoline (Dostinex), the usual drug to make prolactin levels return to normal, but as those weren’t worrying enough (neither for her nor for the subsequent endos that I had) I was told to stop.

Then, a few years later, I stopped taking the pill (on purpose) and having the period (not on purpose) and a PRL check showed an alarming increase: 62.79 ng/ml. It was summer of 2007, I was already in Munich, my new gyn told me to take cabergoline (Dostinex) again. PRL dropped, but my period didn’t show up. So she sent me to another endo, who did a thorough hormone analysis in december, found out that the chickpea wasn’t innocent at all and I was sent eventually to the neurosurgeon two months later.

Right after the surgery (and by “right after” I mean “the following day”), the PRL levels dropped to nearly non-existent. Galactorrhea stopped and I got my period back, on a 29-day regular basis.

prl1

(Not all PRL values that I have are shown, but just the most significant ones)

Apparently, my PRL levels were too low to suggest a PRL-producing adenoma, but it was. It produced both PRL and GH.

November 6, 2008 at 1:06 pm 5 comments


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